Clean-in-place (cip) systems f...

Hey everyone! I’m looking to integrate a Clean-in-Place (CIP) system into my laboratory bioreactors to improve efficiency and sterility. I mainly work with glass, autoclavable bioreactors (3L–10L) for microbial and cell culture applications. Has anyone successfully set up a semi-automated or automated CIP system for lab-scale use? Would love to hear your experiences and recommendations!

Hey! I recently integrated a semi-automated CLEAN-IN-PLACE SYSTEMS  https://brsbiotech.com/catalog/stainless-steel-fermentors-bioreactors/clean-in-place-systems/ into my glass bioreactors (3L-10L) for microbial and cell culture applications, and it's made a huge difference in efficiency and sterility. I went with a setup from BRS Biotech, which provides great flexibility for lab-scale use. The automated cleaning cycles reduce downtime, and I’ve noticed a significant improvement in cleanliness between batches. For anyone looking to optimize, make sure to consider system compatibility with your glass bioreactors and automate as much as possible for consistent results!

Good points! I was thinking of using a mobile CIP skid but wasn’t sure if it would be effective on smaller glass reactors. Do you recommend any specific detergents or CIP validation methods?